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Women and Consumer Culture in Early Twentieth-century Japan: The Department Store, Modernity and Everyday Life

為了解決Rapid development的問題，作者Tamari, Tomoko 這樣論述：

The first thirty years of the twentieth century was a key period in the development of Japanese society, during which it began to face directly the political, economic and cultural power of the West in order to establish a modern Japan that was distinctive from both the West and the rest of Asia. Be

coming modern not only entailed the reform and re-education of the Japanese people into a nation; it also resulted in the reform of everyday life and the redefinition of the people as consumers and citizens. Women, in particular, were at the forefront of these changes and experienced directly the ne

w forms of consumer culture. This book examines this key phase in Japanese modernity and explores how women in Japan played a significant role in shaping the burgeoning Japanese consumer society. It also unveils the cultural myth of docile Japanese women embedded in tradition and examines the ways i

n which women developed a new type of active femininity by becoming modern. The period also saw the beginnings of mass consumption alongside rapid urbanization with the rise of the department store and the growth of mass media. One of the most important Japanese department stores to emerge was Mitsu

koshi, which provided an experimental site for the new tastes and lifestyles of consumer culture and the 'exotica' of western modernity. In effect, the store could be seen as a new form of 'public sphere' for women. Women's magazines and films also provided images and information on the new consumer

culture. The book provides a new account of the development of Japanese consumer culture in the twentieth century and explores the importance of the emergence of a new type of femininity for Japanese women. It will therefore appeal to those studying consumer culture, visual culture, body studies, s

ociology, media and film studies, business studies (retailing), and gender studies.

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An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決Rapid development的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.

Encyclopedia of Malaria

為了解決Rapid development的問題，作者Hommel, Marcel (EDT)/ Kremsner, Peter G. (EDT) 這樣論述：

The Encyclopedia of Malaria represents a vast databank of information about the study of malaria. It provides an overview of the historical, rapid and significant developments that have occurred in malaria research, including the 2002 genome sequencing of Plasmodium falciparum and its mosquito vecto

r, Anopheles gambiae. This work provides a concise source of up-to-date research findings in the form of definitions and essays and present comprehensive coverage of topics from history to findings to diagnosis and treatment, written by recognized malaria researchers with practical experience. It ap

peals to a diverse audience, including malaria researchers, teachers, investigators and public health professionals. After a medical degree in France and a PhD from the University of Liverpool, Marcel Hommel worked in various research institutes, including the National Institute for Medical Resear

ch, the Institut Pasteur and Harvard Medical School. In 1986, he was appointed Professor of Tropical Medicine in Liverpool.His research interests are mainly in the field of malaria immunology and pathophysiology, and he first described antigenic variation in Plasmodium falciparum and the importance

of parasite diversity in the development of immunity. Also interested in the development of immunodiagnostic tests, particularly those applicable in a tropical environment, currently working on a test of cure for visceral leishmaniasis. Over the years, he has supervised 37 research students, taught

and examined on many different courses worldwide.He has been on the editorial board of a number of journals and, for the past 10 years, has been Editor-in-Chief of Malaria Journal.

公有雲端企業資料庫即時同步備援到企業自有機房之研究

為了解決Rapid development的問題，作者周建竹 這樣論述：

由於在近十年來網路通訊技術的快速發展，雲端服務在手機時代已經被各企業和個人所採用，在此平台上，提供的服務，可以使租用戶能快速建構符合他們本身所需要的資料系統，另外在以前雲端服務及網路通訊技術尚未普及的年代，資訊系統備援是有地區距離的限制，而現在，在地端和雲端聯結更緊密的時代，在雲端各應用系統的後端的關聯式資料庫儲存重要的交易資料，其中備援設計更是極為重要。在本論文中研究的目的將以雲端的關聯式資料庫層級即時備援到地端，從可用性、即時性、保密安全性、持久性保存和搬遷性等做探討，本研究所採用的方式為在雲端租用和設定環境和地端架設環境，建構本研究之研究模型，進行雲端到地端在關聯式資料庫層級的備援探討

分析，並使用雲端運算業者Azure的計量統計圖表做資料蒐集及資料分析，呈現雲端硬碟讀寫累積使用量和網路頻寬累積使用量的數據並進行分析和探討，企業將可依照自己業務特性，做出符合最佳化的雲端資料庫備援到地端資料庫方式的決策。